Keith Earls will miss out on Munster's Champions Cup opener away to Racing Metro on Sunday.
The winger is following return to play protocols after suffering a concussion in last weekends PRO12 loss to Leinster.
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It means new signing Jaco Taute comes into the side at outside centre.
Director Rassie Erasmus feels last weekends game will have steeled players for the big occasion.
Elsewhere, a tight hamstring means Johnny Sexton misses Leinsters clash with Castres at the RDS tomorrow.