Munster who've already reached the semi finals make a total of 11 changes to the side that started against Toulon as they take on Edinburgh tomorrow in the Scottish capital.
A new look front row sees James Cronin and John Ryan pack down on either side of Duncan Casey.
Paul O'Connell and Donncha O'Callaghan combine forces in the second row while Tommy O'Donnell and Paddy Butler return to the starting line-up alongside CJ Stander in the back row.
JJ Hanrahan suffered no ill effects from the last 20 minutes of last weekend's encounter in Marseille and partners up with Conor Murray in the half backs.
Denis Hurley and Johne Murphy, both of whom signed new contracts with Munster this week, form the centre partnership.
While Simon Zebo switches to full-back this weekend with Andrew Conway and Gerhard Van Den Heever introduced on the wings.
