New HSE figures show University Hospital Limerick has the highest budgetary overrun of any hospital in Ireland this year.
Up until the end of March, the region's main hospital exceeded its allocated spending limit by €6 million.
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In the first quarter of the year, acute hospitals nationwide breached spending guidelines by €63 million, and the HSE says it faces an "extremely significant" challenge in trying to break even financially this year.
At Ennis General Hospital, spending was €39,000 under budget.
