Conor Murray, Donnacha Ryan, Francis Saili and Mike Sherry have all come through this week's preparations in time to be included in Munster's squad to take on Leicester Tigers on Saturday in Thomond Park.
Head Coach Anthony Foley makes nine changes to the side that started against Newport Gwent Dragons last Sunday.
In the front row James Cronin and BJ Botha return to scrum down on either side of hooker Niall Scannell who makes his first European appearance this weekend.
The returning Donnacha Ryan joins Dave Foley in the second row while Robin Copeland and CJ Stander are named alongside Dave O'Callaghan in the back row.
Named at blindside, this will be Copeland's first Champions Cup start for the province, while Stander returns to captain the side from number 8.
A changed half-back pairing sees Conor Murray and Ian Keatley renew their partnership after Murray successfully rehabbed a bruised bone he sustained during the round one encounter against Treviso.
The further changes to the backline see Francis Saili, Keith Earls and Andrew Conway all named. Francis Saili starts with Denis Hurley in midfield while Simon Zebo is joined by Keith Earls and Andrew Conway in the back three.
Mike Sherry is included in the replacements following on from a knee injury he sustained in the opening round against Treviso while Tyler Bleyendaal is in line to make his European debut if sprung from the bench.
Munster: Andrew Conway; Keith Earls, Francis Saili, Denis Hurley, Simon Zebo; Ian Keatley, Conor Murray; James Cronin, Niall Scannell, BJ Botha; Dave Foley, Donnacha Ryan; Robin Copeland, Dave O'Callaghan, CJ Stander Capt.
Replacements: Mike Sherry, Dave Kilcoyne, John Ryan, Mark Chisholm, Jack O'Donoghue, Tomás O'Leary, Tyler Bleyendaal, Lucas Gonzalez Amorosino.
