Joe Schmidt has named his side for Saturday's opening World Cup Pool D game with Canada.
Luke Fitzgerald has beaten Robbie Henshaw to the position of inside centre, after the Connacht man missed training with an as-yet unspecified injury.
There's no room for Tommy Bowe or Simon Zebo in the back line, with the wings manned by Keith Earls and Dave Kearney.
Cian Healy doesn't start, but is named among the replacements.
The team in full sees Rob Kearney at full back, Dave Kearney and Earls on the wings with Jared Payne and Fitzgerald in the centre.
Conor Murray and Johnny Sexton form the three-quarters.
There's a front row of Jack McGrath, Rory Best and Mike Ross.
Captain Paul O'Connell is partnered in the second row by Iain Henderson.
Peter O'Mahony is blindside flanker, Sean O'Brien on the openside, and Jamie Heaslip is number 8.
Healy is one of three front rows on the bench along with Sean Cronin and Nathan White.
There's no Devin Toner in the matchday 23, with Donnacha Ryan the replacement second row.
Back row cover is provided by Chris Henry, while there's defensive cover in the form of Eoin Reddan, Ian Madigan and Simon Zebo.
